CDK10 (cyclin dependent kinase 10)

2003-12-01  

Identity

HGNC
LOCATION
16q24.3
LOCUSID
ALIAS
ALSAS,PISSLRE
FUSION GENES

Other Information

Locus ID:

NCBI: 8558
MIM: 603464
HGNC: 1770
Ensembl: ENSG00000185324

Variants:

dbSNP: 8558
ClinVar: 8558
TCGA: ENSG00000185324
COSMIC: CDK10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185324ENST00000331006F8W872
ENSG00000185324ENST00000353379Q15131
ENSG00000185324ENST00000502547D6REZ2
ENSG00000185324ENST00000505473Q15131
ENSG00000185324ENST00000508723D6RA59
ENSG00000185324ENST00000510811Q9UHL7
ENSG00000185324ENST00000511415D6RHH3
ENSG00000185324ENST00000512912D6REZ2
ENSG00000185324ENST00000564192H3BT74
ENSG00000185324ENST00000565470H3BSN8
ENSG00000185324ENST00000617879Q15131
ENSG00000185324ENST00000625631Q9UHL7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
242185722013CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.25
221580352012Proyl isomerase Pin1 facilitates ubiquitin-mediated degradation of cyclin-dependent kinase 10 to induce tamoxifen resistance in breast cancer cells.15
222099422012CDK10 functions as a tumor suppressor gene and regulates survivability of biliary tract cancer cells.13
223262702012Clinical and biological significance of Cdk10 in hepatocellular carcinoma.10
263923602015Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report.10
237400912013Promoter hypermethylation contributes to the frequent suppression of the CDK10 gene in human nasopharyngeal carcinomas.9
288863412017CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.8
271047472016STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis.7
198469322009CDK10 is not a target for aberrant DNA methylation in breast cancer.6
262094382015Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study.6

Citation

Dessen P

CDK10 (cyclin dependent kinase 10)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40030/cdk10