CNTN2 (contactin 2)

2003-02-01  

Identity

HGNC
CNTN2
LOCATION
1q32.1
LOCUSID
6900
ALIAS
AXT,FAME5,TAG-1,TAX,TAX1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6900
MIM: 190197
HGNC: 2172
Ensembl: ENSG00000184144

Variants:

dbSNP: 6900
ClinVar: 6900
TCGA: ENSG00000184144
COSMIC: CNTN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184144ENST00000331830Q02246
ENSG00000184144ENST00000331830A0A024R9B4
ENSG00000184144ENST00000532366A0A1W2PPY1
ENSG00000184144ENST00000636312A0A1B0GTL7
ENSG00000184144ENST00000638378Q02246
ENSG00000184144ENST00000638378A0A024R9B4
ENSG00000184144ENST00000638577A0A1W2PR60
ENSG00000184144ENST00000639122A0A1W2PQJ4
ENSG00000184144ENST00000639302Q02246
ENSG00000184144ENST00000639302A0A024R9B4
ENSG00000184144ENST00000639843A0A1W2PPQ9
ENSG00000184144ENST00000639971A0A1W2PQ86
ENSG00000184144ENST00000640326Q02246
ENSG00000184144ENST00000640326A0A024R9B4
ENSG00000184144ENST00000640352A0A1W2PPY1
ENSG00000184144ENST00000640428A0A1W2PQ11

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
NCAM signaling for neurite out-growthREACTOMER-HSA-375165
NCAM1 interactionsREACTOMER-HSA-419037
L1CAM interactionsREACTOMER-HSA-373760
NrCAM interactionsREACTOMER-HSA-447038

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
375652792024Assessment of Bcl-xL, TAX, and HBZ Gene Expression in Adult T cell Leukemia/Lymphoma Patients.0
384600762024Gene-gene interaction network analysis indicates CNTN2 is a candidate gene for idiopathic generalized epilepsy.0
375652792024Assessment of Bcl-xL, TAX, and HBZ Gene Expression in Adult T cell Leukemia/Lymphoma Patients.0
384600762024Gene-gene interaction network analysis indicates CNTN2 is a candidate gene for idiopathic generalized epilepsy.0
367340722023The molecular mechanism of γ-aminobutyric acid against AD: the role of CEBPα/circAPLP2/miR-671-5p in regulating CNTN1/2 expression.1
367340722023The molecular mechanism of γ-aminobutyric acid against AD: the role of CEBPα/circAPLP2/miR-671-5p in regulating CNTN1/2 expression.1
328067912020Contactin-1 Is Reduced in Cerebrospinal Fluid of Parkinson's Disease Patients and Is Present within Lewy Bodies.7
328067912020Contactin-1 Is Reduced in Cerebrospinal Fluid of Parkinson's Disease Patients and Is Present within Lewy Bodies.7
316230792019Cord Blood-Derived Exosomal CNTN2 and BDNF: Potential Molecular Markers for Brain Health of Neonates at Risk for Iron Deficiency.9
316230792019Cord Blood-Derived Exosomal CNTN2 and BDNF: Potential Molecular Markers for Brain Health of Neonates at Risk for Iron Deficiency.9
296846832018Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach.38
298591292018Contactin-2, a synaptic and axonal protein, is reduced in cerebrospinal fluid and brain tissue in Alzheimer's disease.10
296846832018Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach.38
298591292018Contactin-2, a synaptic and axonal protein, is reduced in cerebrospinal fluid and brain tissue in Alzheimer's disease.10
285332672017The Kv1-associated molecules TAG-1 and Caspr2 are selectively targeted to the axon initial segment in hippocampal neurons.14

Citation

Dessen P

CNTN2 (contactin 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40118/css/js/lib/js/web-card-gene.js