CSF1 (colony stimulating factor 1)

2003-08-01  

Identity

HGNC
CSF1
LOCATION
1p13.3
LOCUSID
1435
ALIAS
CSF-1,MCSF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1435
MIM: 120420
HGNC: 2432
Ensembl: ENSG00000184371

Variants:

dbSNP: 1435
ClinVar: 1435
TCGA: ENSG00000184371
COSMIC: CSF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184371ENST00000329608P09603
ENSG00000184371ENST00000357302H7BY18
ENSG00000184371ENST00000369801P09603
ENSG00000184371ENST00000369802P09603
ENSG00000184371ENST00000420111P09603
ENSG00000184371ENST00000488198E9PJA2
ENSG00000184371ENST00000525659E9PKP4
ENSG00000184371ENST00000527192E9PQ08

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Hematopoietic cell lineageKEGGko04640
Cytokine-cytokine receptor interactionKEGGhsa04060
Hematopoietic cell lineageKEGGhsa04640
Osteoclast differentiationKEGGko04380
Osteoclast differentiationKEGGhsa04380
Rheumatoid arthritisKEGGko05323
Rheumatoid arthritisKEGGhsa05323
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
TNF signaling pathwayKEGGhsa04668
TNF signaling pathwayKEGGko04668
Ras signaling pathwayKEGGhsa04014
Rap1 signaling pathwayKEGGhsa04015
Rap1 signaling pathwayKEGGko04015
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Interleukin-10 signalingREACTOMER-HSA-6783783

References

Pubmed IDYearTitleCitations
381426402024Multiple cytokine analyses identify CSF1 as a robust biomarker for predicting postoperative recurrence in chronic rhinosinusitis with nasal polyps.0
381427812024Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages.0
381426402024Multiple cytokine analyses identify CSF1 as a robust biomarker for predicting postoperative recurrence in chronic rhinosinusitis with nasal polyps.0
381427812024Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages.0
363775082023RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12.13
365044572023A novel colony-stimulating factor 1 (CSF1) translocation  involving human endogenous retroviral element in a tenosynovial giant cell tumor.2
369169282023Cathepsin C promotes colorectal cancer metastasis by regulating immune escape through upregulating CSF1.6
370974992023Important oncogenic and immunogenic roles of SPP1 and CSF1 in hepatocellular carcinoma.3
372492912023Increased expression of CSF1 in patients with eosinophilic asthma.0
374796942023ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis.2
376386872023Inhibition of inflammation and infiltration of M2 macrophages in NSCLC through the ATF3/CSF1 axis: Role of miR-27a-3p.1
376766422023p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression.2
381592542023M-CSF secreted by gastric cancer cells exacerbates the progression of gastric cancer by increasing the expression of SHP2 in tumor-associated macrophages.0
363775082023RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12.13
365044572023A novel colony-stimulating factor 1 (CSF1) translocation  involving human endogenous retroviral element in a tenosynovial giant cell tumor.2

Citation

Dessen P

CSF1 (colony stimulating factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40160/gene-fusions-explorer/haematological-explorer/js/_common.js