CTNNBL1 (catenin beta like 1)

2003-05-01  

Identity

HGNC
CTNNBL1
LOCATION
20q11.23
LOCUSID
56259
ALIAS
C20orf33,NAP,P14L,PP8304,dJ633O20.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 56259
MIM: 611537
HGNC: 15879
Ensembl: ENSG00000132792

Variants:

dbSNP: 56259
ClinVar: 56259
TCGA: ENSG00000132792
COSMIC: CTNNBL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132792ENST00000361383Q8WYA6
ENSG00000132792ENST00000373469Q8WYA6
ENSG00000132792ENST00000373473Q8WYA6
ENSG00000132792ENST00000405275Q8WYA6
ENSG00000132792ENST00000447935A2A2P1
ENSG00000132792ENST00000621317A0A087WUB9
ENSG00000132792ENST00000628103Q8WYA6

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Spliceosome, Prp19/CDC5L complexKEGGhsa_M00353
Spliceosome, Prp19/CDC5L complexKEGGM00353
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371080602023Regulation of UV-B-Induced Inflammatory Mediators by Activity-Dependent Neuroprotective Protein (ADNP)-Derived Peptide (NAP) in Corneal Epithelium.0
371080602023Regulation of UV-B-Induced Inflammatory Mediators by Activity-Dependent Neuroprotective Protein (ADNP)-Derived Peptide (NAP) in Corneal Epithelium.0
324847992020Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID.9
329617082020Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer.91
324847992020Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID.9
329617082020Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer.91
285014612017Spliceosome-associated factor CTNNBL1 promotes proliferation and invasion in ovarian cancer.18
285014612017Spliceosome-associated factor CTNNBL1 promotes proliferation and invasion in ovarian cancer.18
267333792016Polymorphisms in Wnt signaling pathway genes are associated with peak bone mineral density, lean mass, and fat mass in Chinese male nuclear families.9
267333792016Polymorphisms in Wnt signaling pathway genes are associated with peak bone mineral density, lean mass, and fat mass in Chinese male nuclear families.9
261307212015CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.7
261307212015CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.7
242696832014Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin α.4
245987472014Structural insights into the novel ARM-repeat protein CTNNBL1 and its association with the hPrp19-CDC5L complex.3
252682582014No association between CTNNBL1 and episodic memory performance.2

Citation

Dessen P

CTNNBL1 (catenin beta like 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40196/img/teaching-explorer/js/web-card-_common.js