CTNND2 (catenin delta 2)

2003-02-01  

Identity

HGNC
CTNND2
LOCATION
5p15.2
LOCUSID
1501
ALIAS
GT24,NPRAP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1501
MIM: 604275
HGNC: 2516
Ensembl: ENSG00000169862

Variants:

dbSNP: 1501
ClinVar: 1501
TCGA: ENSG00000169862
COSMIC: CTNND2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169862ENST00000304623Q9UQB3
ENSG00000169862ENST00000458100D6R9A8
ENSG00000169862ENST00000502551D6RC65
ENSG00000169862ENST00000503622B4DRK2
ENSG00000169862ENST00000504499D6RHE9
ENSG00000169862ENST00000508761D6RBA8
ENSG00000169862ENST00000511377E7EPC8
ENSG00000169862ENST00000513588E9PHB5
ENSG00000169862ENST00000513598D6RF55

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
189403112008Recurrent CNVs disrupt three candidate genes in schizophrenia patients.107
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
191655272009Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.56
176870282007Synaptic anchorage of AMPA receptors by cadherins through neural plakophilin-related arm protein AMPA receptor-binding protein complexes.46
210950092011Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese.44
184210762008A genome-wide scan maps a novel high myopia locus to 5p15.38
162261022005Increased expression of delta-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cancer.37
229844392012δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes.21
189788172009Increased nucleotide polymorphic changes in the 5'-untranslated region of delta-catenin (CTNND2) gene in prostate cancer.19

Citation

Dessen P

CTNND2 (catenin delta 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40198/ctnnd2