CTSE (cathepsin E)

2003-06-01  

Identity

HGNC
CTSE
LOCATION
1q32.1
LOCUSID
1510
ALIAS
CATE

Other Information

Locus ID:

NCBI: 1510
MIM: 116890
HGNC: 2530
Ensembl: ENSG00000196188

Variants:

dbSNP: 1510
ClinVar: 1510
TCGA: ENSG00000196188
COSMIC: CTSE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196188ENST00000358184P14091
ENSG00000196188ENST00000360218P14091

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
351819762022Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease.9
351819762022Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease.9
302782642019The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal Enlargement in the Wall of the Abdominal Aortic Aneurysm.7
302782642019The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal Enlargement in the Wall of the Abdominal Aortic Aneurysm.7
253487782015High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma.10
253487782015High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma.10
242423302014Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.13
244649562014Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.10
252395632014Cathepsin E promotes pulmonary emphysema via mitochondrial fission.19
242423302014Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.13
244649562014Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.10
252395632014Cathepsin E promotes pulmonary emphysema via mitochondrial fission.19
234510822013Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.24
234510822013Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.24
216649912012Emerging roles of cathepsin E in host defense mechanisms.15

Citation

Dessen P

CTSE (cathepsin E)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40204/deep-insight-explorer/js/lib/bootstrap.min.js