DIAPH2 (diaphanous related formin 2)

2003-05-01  

Identity

HGNC
LOCATION
Xq21.33
LOCUSID
ALIAS
DIA,DIA2,DRF2,POF,POF2,POF2A
FUSION GENES

Other Information

Locus ID:

NCBI: 1730
MIM: 300108
HGNC: 2877
Ensembl: ENSG00000147202

Variants:

dbSNP: 1730
ClinVar: 1730
TCGA: ENSG00000147202
COSMIC: DIAPH2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147202ENST00000324765O60879
ENSG00000147202ENST00000355827A6NML8
ENSG00000147202ENST00000373049O60879
ENSG00000147202ENST00000373054C9J6U3
ENSG00000147202ENST00000373061K4DI95

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Regulation of actin cytoskeletonKEGGko04810
Regulation of actin cytoskeletonKEGGhsa04810
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
388447232024DIAPH2 gene polymorphisms and laryngeal cancer risk in men.0
388447232024DIAPH2 gene polymorphisms and laryngeal cancer risk in men.0
342999352021DIAPH2, PTPRD and HIC1 Gene Polymorphisms and Laryngeal Cancer Risk.5
342999352021DIAPH2, PTPRD and HIC1 Gene Polymorphisms and Laryngeal Cancer Risk.5
305934402019Association between early embryo morphokinetics plus cumulus cell gene expression and assisted reproduction outcomes in polycystic ovary syndrome women.9
307931642019DIAPH2 alterations increase cellular motility and may contribute to the metastatic potential of laryngeal squamous cell carcinoma.8
305934402019Association between early embryo morphokinetics plus cumulus cell gene expression and assisted reproduction outcomes in polycystic ovary syndrome women.9
307931642019DIAPH2 alterations increase cellular motility and may contribute to the metastatic potential of laryngeal squamous cell carcinoma.8
295965202018Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2).19
295965202018Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2).19
287609852017Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport.35
287609852017Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport.35
240373432014Identification of genes promoting skin youthfulness by genome-wide association study.5
244036062014Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration.31
240373432014Identification of genes promoting skin youthfulness by genome-wide association study.5

Citation

Dessen P

DIAPH2 (diaphanous related formin 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40307/css/js/lib/favicon/favicon-16x16.png