ETV7 (ETS variant transcription factor 7)

2003-02-01  

Identity

HGNC
ETV7
LOCATION
6p21.31
LOCUSID
51513
ALIAS
TEL-2,TEL2,TELB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51513
MIM: 605255
HGNC: 18160
Ensembl: ENSG00000010030

Variants:

dbSNP: 51513
ClinVar: 51513
TCGA: ENSG00000010030
COSMIC: ETV7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000010030ENST00000339796Q9Y603
ENSG00000010030ENST00000340181Q9Y603
ENSG00000010030ENST00000373737Q9Y603
ENSG00000010030ENST00000373738Q9Y603
ENSG00000010030ENST00000538992Q9Y603
ENSG00000010030ENST00000615781Q9Y603
ENSG00000010030ENST00000620358Q9Y603
ENSG00000010030ENST00000627426Q9Y603

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Dorso-ventral axis formationKEGGko04320
Dorso-ventral axis formationKEGGhsa04320
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
157438322005The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis.20
263350512015TEL2 suppresses metastasis by down-regulating SERPINE1 in nasopharyngeal carcinoma.18
302589852018ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer.9
300252292018ETV7-Mediated DNAJC15 Repression Leads to Doxorubicin Resistance in Breast Cancer Cells.2
304785272019Establishment of a transgenic mouse to model ETV7 expressing human tumors.1
292795242018Transcriptional Analysis of Endothelial Cell Alternation Induced by Atrial Natriuretic Polypeptide in Human Umbilical Vein Endothelial Cells.0

Citation

Dessen P

ETV7 (ETS variant transcription factor 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40506/etv7-(ets-variant-transcription-factor-7)