FABP3 (fatty acid binding protein 3)

2003-02-01  

Identity

HGNC
FABP3
LOCATION
1p35.2
LOCUSID
2170
ALIAS
FABP11,H-FABP,M-FABP,MDGI,O-FABP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2170
MIM: 134651
HGNC: 3557
Ensembl: ENSG00000121769

Variants:

dbSNP: 2170
ClinVar: 2170
TCGA: ENSG00000121769
COSMIC: FABP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121769ENST00000373713P05413
ENSG00000121769ENST00000373713A0A384MDY5
ENSG00000121769ENST00000482018S4R371
ENSG00000121769ENST00000498148S4R3A2

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
PPAR signaling pathwayKEGGhsa03320
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysisREACTOMER-HSA-163560

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382696332024Fatty acid-binding protein-3 and renal function decline in patients with chronic coronary syndrome.0
387771422024Fatty acid binding to the human transport proteins FABP3, FABP4, and FABP5 from a Ligand's perspective.0
382696332024Fatty acid-binding protein-3 and renal function decline in patients with chronic coronary syndrome.0
387771422024Fatty acid binding to the human transport proteins FABP3, FABP4, and FABP5 from a Ligand's perspective.0
364817332023Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons.6
366811242023Loss of fatty acid binding protein 3 ameliorates lipopolysaccharide-induced inflammation and endothelial dysfunction.3
368031202023Plasma Galectin-3 and H-FABP correlate with poor physical performance in patients with congestive heart failure.1
371891232023Evaluation of circulating insulin-like growth factor-1, heart-type fatty acid-binding protein, and endotrophin levels as prognostic markers of COVID-19 infection severity.0
377870632023Circulating H-FABP as a biomarker of frailty in patients with chronic heart failure.0
377887262023Anti bacterial function of secreted human FABP3.0
378024852023Serum levels of soluble suppression of tumorigenicity 2 (sST2) and heart-type fatty acid binding protein (H-FABP) independently predict in-hospital mortality in geriatric patients with COVID-19.0
364817332023Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons.6
366811242023Loss of fatty acid binding protein 3 ameliorates lipopolysaccharide-induced inflammation and endothelial dysfunction.3
368031202023Plasma Galectin-3 and H-FABP correlate with poor physical performance in patients with congestive heart failure.1
371891232023Evaluation of circulating insulin-like growth factor-1, heart-type fatty acid-binding protein, and endotrophin levels as prognostic markers of COVID-19 infection severity.0

Citation

Dessen P

FABP3 (fatty acid binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40524/gene-fusions-explorer/js/lib/jquery-3.5.1.min.js