GADD45B (growth arrest and DNA damage inducible beta)

2003-08-01  

Identity

HGNC
GADD45B
LOCATION
19p13.3
LOCUSID
4616
ALIAS
GADD45BETA,MYD118

Other Information

Locus ID:

NCBI: 4616
MIM: 604948
HGNC: 4096
Ensembl: ENSG00000099860

Variants:

dbSNP: 4616
ClinVar: 4616
TCGA: ENSG00000099860
COSMIC: GADD45B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099860ENST00000215631O75293
ENSG00000099860ENST00000585359K7EM97
ENSG00000099860ENST00000587345K7EPQ8
ENSG00000099860ENST00000587887Q6IX74
ENSG00000099860ENST00000593043Q6IX74

Expression (GTEx)

0
100
200
300
400
500
600
700
800
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
Cell cycleKEGGko04110
p53 signaling pathwayKEGGko04115
ApoptosisKEGGko04210
MAPK signaling pathwayKEGGhsa04010
Cell cycleKEGGhsa04110
p53 signaling pathwayKEGGhsa04115
ApoptosisKEGGhsa04210
NF-kappa B signaling pathwayKEGGhsa04064
NF-kappa B signaling pathwayKEGGko04064
FoxO signaling pathwayKEGGhsa04068

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386143062024GADD45B in the ventral hippocampal CA1 modulates aversive memory acquisition and spatial cognition.0
386143062024GADD45B in the ventral hippocampal CA1 modulates aversive memory acquisition and spatial cognition.0
375345852023Expression of GADD45B in Renal Tissue of Children with IgA Nephropathy and Correlation with Mesangial Hypercellularity.0
376087942023GADD45B regulates the carcinogenesis process of chronic atrophic gastritis and the metabolic pathways of gastric cancer.1
376624802023Key Roles of p53 Signaling Pathway-Related Factors GADD45B and SERPINE1 in the Occurrence and Development of Gastric Cancer.0
380701412023Has-miR-300-GADD45B promotes melanoma growth via cell cycle.0
375345852023Expression of GADD45B in Renal Tissue of Children with IgA Nephropathy and Correlation with Mesangial Hypercellularity.0
376087942023GADD45B regulates the carcinogenesis process of chronic atrophic gastritis and the metabolic pathways of gastric cancer.1
376624802023Key Roles of p53 Signaling Pathway-Related Factors GADD45B and SERPINE1 in the Occurrence and Development of Gastric Cancer.0
380701412023Has-miR-300-GADD45B promotes melanoma growth via cell cycle.0
348423212022Single-cell transcriptomics identifies Gadd45b as a regulator of herpesvirus-reactivating neurons.13
348423212022Single-cell transcriptomics identifies Gadd45b as a regulator of herpesvirus-reactivating neurons.13
342724242021Growth arrest and DNA damage-inducible proteins (GADD45) in psoriasis.6
342724242021Growth arrest and DNA damage-inducible proteins (GADD45) in psoriasis.6
324258872020GADD45B Transcript Is a Prognostic Marker in Papillary Thyroid Carcinoma Patients Treated With Total Thyroidectomy and Radioiodine Therapy.10

Citation

Dessen P

GADD45B (growth arrest and DNA damage inducible beta)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40666/gene-explorer/favicon/apple-touch-icon.png