GNB1L (G protein subunit beta 1 like)

GNB1L (G protein subunit beta 1 like)

2003-05-01 Affiliation

Identity

HGNC

LOCATION

22q11.21

LOCUSID

ALIAS

DGCRK3,FKSG1,GY2,WDR14,WDVCF

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 54584
MIM: 610778
HGNC: 4397
Ensembl: ENSG00000185838

Variants:

dbSNP: 54584
ClinVar: 54584
TCGA: ENSG00000185838
COSMIC: GNB1L

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000185838	ENST00000329517	Q9BYB4
ENSG00000185838	ENST00000403325	Q9BYB4
ENSG00000185838	ENST00000405009	Q9BYB4
ENSG00000185838	ENST00000453108	C9JPQ6

Expression (GTEx)

0

1

2

3

4

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

PharmGKB

Entity ID	Name	Type	Evidence	Association	PK	PD	PMIDs
PA33384	PLCB1	Gene	Pathway	associated
PA33385	PLCB2	Gene	Pathway	associated
PA33386	PLCB3	Gene	Pathway	associated
PA33387	PLCB4	Gene	Pathway	associated

References

Pubmed ID	Year	Title	Citations
33932639	2021	Sequencing of the coding regions of GNBIL on chromosome 22q11.2 as a risk gene of schizophrenia.	0
33932639	2021	Sequencing of the coding regions of GNBIL on chromosome 22q11.2 as a risk gene of schizophrenia.	0
24831436	2015	The schizophrenia/bipolar disorder candidate gene GNB1L is regulated in human temporal cortex by a cis-acting element located within the 3'-region.	1
24831436	2015	The schizophrenia/bipolar disorder candidate gene GNB1L is regulated in human temporal cortex by a cis-acting element located within the 3'-region.	1
20538345	2011	Association study between GNB1L and three major mental disorders in Chinese Han populations.	6
20538345	2011	Association study between GNB1L and three major mental disorders in Chinese Han populations.	6
20538345	2011	Association study between GNB1L and three major mental disorders in Chinese Han populations.	6
20538345	2011	Association study between GNB1L and three major mental disorders in Chinese Han populations.	6
19011233	2010	Supportive evidence for reduced expression of GNB1L in schizophrenia.	13
19011233	2010	Supportive evidence for reduced expression of GNB1L in schizophrenia.	13
20860462	2010	β-blocker therapy and heart rate control during exercise testing in the general population: role of a common G-protein β-3 subunit variant.	3
19011233	2010	Supportive evidence for reduced expression of GNB1L in schizophrenia.	13
19011233	2010	Supportive evidence for reduced expression of GNB1L in schizophrenia.	13
20860462	2010	β-blocker therapy and heart rate control during exercise testing in the general population: role of a common G-protein β-3 subunit variant.	3
18003636	2008	Strong evidence that GNB1L is associated with schizophrenia.	28

Citation

Dessen P

GNB1L (G protein subunit beta 1 like)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40729/css/img/js/_common.js