YTHDF2 (YTH N6-methyladenosine RNA binding protein 2)

2003-06-01  

Identity

HGNC
LOCATION
1p35.3
LOCUSID
ALIAS
CAHL,DF2,HGRG8,NY-REN-2
FUSION GENES

Other Information

Locus ID:

NCBI: 51441
MIM: 610640
HGNC: 31675
Ensembl: ENSG00000198492

Variants:

dbSNP: 51441
ClinVar: 51441
TCGA: ENSG00000198492
COSMIC: YTHDF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198492ENST00000373812Q9Y5A9
ENSG00000198492ENST00000474884S4R3J8
ENSG00000198492ENST00000496288S4R3V3
ENSG00000198492ENST00000541996Q9Y5A9
ENSG00000198492ENST00000542507Q9Y5A9

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379339092024WTAP enhances the instability of SYTL1 mRNA caused by YTHDF2 in bladder cancer.1
380136002024METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy.2
381901282024FOXM1 Participates in Scleral Remodeling in Myopia by Upregulating APOA1 Expression Through METTL3/YTHDF2.0
382471712024YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD-L1/VEGFA Axis.2
383809572024FTO promotes the progression of retinoblastoma through YTHDF2-dependent N6-methyladenosine modification in E2F3.0
384621652024YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation.0
385486692024Negative Regulation of LINC01013 by METTL3 and YTHDF2 Enhances the Osteogenic Differentiation of Senescent Pre-Osteoblast Cells Induced by Hydrogen Peroxide.0
386165122024YTHDF2 promotes gastric cancer progression and enhances chemoradiotherapy resistance.0
379339092024WTAP enhances the instability of SYTL1 mRNA caused by YTHDF2 in bladder cancer.1
380136002024METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy.2
381901282024FOXM1 Participates in Scleral Remodeling in Myopia by Upregulating APOA1 Expression Through METTL3/YTHDF2.0
382471712024YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD-L1/VEGFA Axis.2
383809572024FTO promotes the progression of retinoblastoma through YTHDF2-dependent N6-methyladenosine modification in E2F3.0
384621652024YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation.0
385486692024Negative Regulation of LINC01013 by METTL3 and YTHDF2 Enhances the Osteogenic Differentiation of Senescent Pre-Osteoblast Cells Induced by Hydrogen Peroxide.0

Citation

Dessen P

YTHDF2 (YTH N6-methyladenosine RNA binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40815/tumors-explorer/css/js/lib/all.min.js