FCRL4 (Fc receptor like 4)

2003-02-01  

Identity

HGNC
LOCATION
1q23.1
LOCUSID
ALIAS
CD307d,FCRH4,IGFP2,IRTA1
FUSION GENES

Other Information

Locus ID:

NCBI: 83417
MIM: 605876
HGNC: 18507
Ensembl: ENSG00000163518

Variants:

dbSNP: 83417
ClinVar: 83417
TCGA: ENSG00000163518
COSMIC: FCRL4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163518ENST00000271532Q96PJ5

Expression (GTEx)

0
1
2
3

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
195926452009Atypical memory B cells are greatly expanded in individuals living in a malaria-endemic area.146
161576852005Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells.112
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
224912542012Cutting edge: human FcRL4 and FcRL5 are receptors for IgA and IgG.48
241627742013The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression.44
219084282011FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling.41
128813172003Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT).30
119297512002IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells.29
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
227163042012IRTA1 is selectively expressed in nodal and extranodal marginal zone lymphomas.17

Citation

Dessen P

FCRL4 (Fc receptor like 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40995/fcrl4-(fc-receptor-like-4)