FBXO42 (F-box protein 42)

2003-05-01  

Identity

HGNC
LOCATION
1p36.13
LOCUSID
ALIAS
Fbx42,JFK
FUSION GENES

Other Information

Locus ID:

NCBI: 54455
MIM: 609109
HGNC: 29249
Ensembl: ENSG00000037637

Variants:

dbSNP: 54455
ClinVar: 54455
TCGA: ENSG00000037637
COSMIC: FBXO42

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000037637ENST00000375592Q6P3S6
ENSG00000037637ENST00000375592A0A024QZB0
ENSG00000037637ENST00000444116X6RKU3
ENSG00000037637ENST00000456164X6RKU3

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
315497672020A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma.11
315497672020A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma.11
257926012015SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer.27
257926012015SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer.27
240636882013Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease.1
240636882013Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease.1
211270742011Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.14
211270742011Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.14
195093322009JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.48
195093322009JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.48

Citation

Dessen P

FBXO42 (F-box protein 42)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41064/css/favicon/apple-touch-icon.png