KISS1 (KiSS-1 metastasis suppressor)

2003-02-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
HH13,KiSS-1
FUSION GENES

Other Information

Locus ID:

NCBI: 3814
MIM: 603286
HGNC: 6341
Ensembl: ENSG00000170498

Variants:

dbSNP: 3814
ClinVar: 3814
TCGA: ENSG00000170498
COSMIC: KISS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170498ENST00000367194Q15726
ENSG00000170498ENST00000625357A0A0D9SES6

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381554902024KISS-1 knockdown inhibits cell growth, migration, and invasion in HTR-8/SVneo cells by regulating the GRP54-mediated PI3K/AKT signaling pathway.0
383410342024STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway.0
389482872024[Notch1/Akt/Foxo1 Pathway Regulated by Kisspeptin Is Involved in Endometrial Decidualization in Patients With Recurrent Spontaneous Abortion].0
381554902024KISS-1 knockdown inhibits cell growth, migration, and invasion in HTR-8/SVneo cells by regulating the GRP54-mediated PI3K/AKT signaling pathway.0
383410342024STAT4 targets KISS1 to inhibit the oxidative damage, inflammation and neuronal apoptosis in experimental PD models by inactivating the MAPK pathway.0
389482872024[Notch1/Akt/Foxo1 Pathway Regulated by Kisspeptin Is Involved in Endometrial Decidualization in Patients With Recurrent Spontaneous Abortion].0
368283042023Association of the KISS1, LIN28B, VDR and ERα gene polymorphisms with early and fast puberty in Chinese girls.0
368548222023KISS1 Gene Variations and Susceptibility to Idiopathic Recurrent Pregnancy Loss.2
370470302023Kisspeptin-10 Mitigates α-Synuclein-Mediated Mitochondrial Apoptosis in SH-SY5Y-Derived Neurons via a Kisspeptin Receptor-Independent Manner.0
371052332023Physiological and pathological roles of locally expressed kisspeptin and KISS1R in the endometrium.1
377025492023Effects of KISS1 structural polymorphism on the risk of polycystic ovary syndrome and reproductive hormones in Iraqi women who take metformin.0
379685642023Kisspeptin-10 increases collagen content in the myocardium by focal adhesion kinase activity.0
368283042023Association of the KISS1, LIN28B, VDR and ERα gene polymorphisms with early and fast puberty in Chinese girls.0
368548222023KISS1 Gene Variations and Susceptibility to Idiopathic Recurrent Pregnancy Loss.2
370470302023Kisspeptin-10 Mitigates α-Synuclein-Mediated Mitochondrial Apoptosis in SH-SY5Y-Derived Neurons via a Kisspeptin Receptor-Independent Manner.0

Citation

Dessen P

KISS1 (KiSS-1 metastasis suppressor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41072/css/lib/deep-insight-explorer/favicon/favicon-32x32.png