MAPRE3 (microtubule associated protein RP/EB family member 3)

2003-06-01  

Identity

HGNC
MAPRE3
LOCATION
2p23.3
LOCUSID
22924
ALIAS
EB3,EBF3,EBF3-S,RP3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22924
MIM: 605788
HGNC: 6892
Ensembl: ENSG00000084764

Variants:

dbSNP: 22924
ClinVar: 22924
TCGA: ENSG00000084764
COSMIC: MAPRE3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000084764ENST00000233121Q9UPY8
ENSG00000084764ENST00000402218Q9UPY8
ENSG00000084764ENST00000405074Q9UPY8
ENSG00000084764ENST00000458529C9JB30
ENSG00000084764ENST00000648289Q9UPY8

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381994792024MAPRE3 as an epigenetic target of EZH2 restricts ovarian cancer proliferation in vitro and in vivo.0
381994792024MAPRE3 as an epigenetic target of EZH2 restricts ovarian cancer proliferation in vitro and in vivo.0
324217022020NMR resonance assignment and structure prediction of the C-terminal domain of the microtubule end-binding protein 3.2
324217022020NMR resonance assignment and structure prediction of the C-terminal domain of the microtubule end-binding protein 3.2
304667862019PKA-dependent phosphorylation of IP3K-A at Ser119 regulates a binding affinity with EB3.1
315423212019Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.64
304667862019PKA-dependent phosphorylation of IP3K-A at Ser119 regulates a binding affinity with EB3.1
315423212019Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.64
283190652017The drebrin/EB3 pathway drives invasive activity in prostate cancer.7
288145702017EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.39
288650142017Phosphorylation of Drebrin and Its Role in Neuritogenesis.5
283190652017The drebrin/EB3 pathway drives invasive activity in prostate cancer.7
288145702017EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.39
288650142017Phosphorylation of Drebrin and Its Role in Neuritogenesis.5
244784522014Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics.9

Citation

Dessen P

MAPRE3 (microtubule associated protein RP/EB family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41298/gene-fusions/teaching-explorer/js/lib/all.min.js