MMP1 (matrix metallopeptidase 1)

2003-02-01  

Identity

HGNC
MMP1
LOCATION
11q22.2
LOCUSID
4312
ALIAS
CLG,CLGN

Other Information

Locus ID:

NCBI: 4312
MIM: 120353
HGNC: 7155
Ensembl: ENSG00000196611

Variants:

dbSNP: 4312
ClinVar: 4312
TCGA: ENSG00000196611
COSMIC: MMP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196611ENST00000315274P03956

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
Bladder cancerKEGGko05219
PPAR signaling pathwayKEGGhsa03320
Pathways in cancerKEGGhsa05200
Bladder cancerKEGGhsa05219
Rheumatoid arthritisKEGGko05323
Rheumatoid arthritisKEGGhsa05323
Metabolism of proteinsREACTOMER-HSA-392499
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)REACTOMER-HSA-381426
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Basigin interactionsREACTOMER-HSA-210991
Extracellular matrix organizationREACTOMER-HSA-1474244
Degradation of the extracellular matrixREACTOMER-HSA-1474228
Activation of Matrix MetalloproteinasesREACTOMER-HSA-1592389
Collagen degradationREACTOMER-HSA-1442490
Interleukin-4 and 13 signalingREACTOMER-HSA-6785807
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

References

Pubmed IDYearTitleCitations
381480932024Association of Matrix Metalloproteinase-1 Promoter Polymorphisms With Asthma Risk.0
385140572024Elevated MMP1 Expression in Carcinoma-Associated Fibroblasts of Breast Cancer Contributes to Tumor Progression and Unfavorable Prognosis.0
385279832024MMP1, MMP9, MMP11 and MMP13 in melanoma and its metastasis - key points in understanding the mechanisms and celerity of tumor dissemination.1
381480932024Association of Matrix Metalloproteinase-1 Promoter Polymorphisms With Asthma Risk.0
385140572024Elevated MMP1 Expression in Carcinoma-Associated Fibroblasts of Breast Cancer Contributes to Tumor Progression and Unfavorable Prognosis.0
385279832024MMP1, MMP9, MMP11 and MMP13 in melanoma and its metastasis - key points in understanding the mechanisms and celerity of tumor dissemination.1
361617462023Mechanism of the Early Catalytic Events in the Collagenolysis by Matrix Metalloproteinase-1.4
364425272023Genetic screening of MMP1 as a potential pathogenic gene in chronic obstructive pulmonary disease.2
370054972023Involvement of matrix metalloproteinase 1 and urokinase-type plasminogen activator in the PKCα-p38 MAPK pathway-mediated progression of human liver cancer cells.0
373281012023Increased Matrix Metalloproteinase-1 Activation Enhances Disruption and Regression of k-RasV12-Expressing Arteriovenous Malformation-Like Vessels.0
373374002023A decrease of mitochondrial ubiquitin ligase increases the secretion of matrix metalloproteinase-1 by dermal fibroblasts through the induction of ER stress.0
377052322023N-acetyltransferase 10 promotes the progression of oral squamous cell carcinoma through N4-acetylcytidine RNA acetylation of MMP1 mRNA.2
361617462023Mechanism of the Early Catalytic Events in the Collagenolysis by Matrix Metalloproteinase-1.4
364425272023Genetic screening of MMP1 as a potential pathogenic gene in chronic obstructive pulmonary disease.2
370054972023Involvement of matrix metalloproteinase 1 and urokinase-type plasminogen activator in the PKCα-p38 MAPK pathway-mediated progression of human liver cancer cells.0

Citation

Dessen P

MMP1 (matrix metallopeptidase 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41387/deep-insight-explorer/favicon/js/lib/popper.js