MMP21 (matrix metallopeptidase 21)

2003-05-01  

Identity

HGNC
LOCATION
10q26.2
LOCUSID
ALIAS
HTX7,MMP-21

Other Information

Locus ID:

NCBI: 118856
MIM: 608416
HGNC: 14357
Ensembl: ENSG00000154485

Variants:

dbSNP: 118856
ClinVar: 118856
TCGA: ENSG00000154485
COSMIC: MMP21

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154485ENST00000368808Q8N119
ENSG00000154485ENST00000651834A0A494C0E5
ENSG00000154485ENST00000651977A0A494C1J6
ENSG00000154485ENST00000652044A0A494C1E5

Expression (GTEx)

0
1
2

References

Pubmed IDYearTitleCitations
264370282015MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates.21
264298892015A human laterality disorder caused by a homozygous deleterious mutation in MMP21.13
178738962007Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma.10
169842592006MMP-21 is expressed by macrophages and fibroblasts in vivo and in culture.8
232751142013Increased MMP-21 expression is associated with poor overall survival of patients with gastric cancer.8
187685252008No association of MMP-7, MMP-8, and MMP-21 polymorphisms with the risk of hepatocellular carcinoma in a Chinese population.7
187685252008No association of MMP-7, MMP-8, and MMP-21 polymorphisms with the risk of hepatocellular carcinoma in a Chinese population.7
199212522009Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma.6
186334362009Matrix metalloproteinase-21 expression is associated with keratinocyte differentiation and upregulated by retinoic acid in HaCaT cells.5
216565252011Identification of high-risk stage II and stage III colorectal cancer by analysis of MMP-21 expression.4

Citation

Dessen P

MMP21 (matrix metallopeptidase 21)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41398/mmp21