MYO18B (myosin XVIIIB)

2003-02-01  

Identity

HGNC
MYO18B
LOCATION
22q12.1
LOCUSID
84700
ALIAS
KFS4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84700
MIM: 607295
HGNC: 18150
Ensembl: ENSG00000133454

Variants:

dbSNP: 84700
ClinVar: 84700
TCGA: ENSG00000133454
COSMIC: MYO18B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133454ENST00000335473Q8IUG5
ENSG00000133454ENST00000407587Q8IUG5
ENSG00000133454ENST00000536101Q8IUG5
ENSG00000133454ENST00000539302F5H6I8
ENSG00000133454ENST00000540454A0A2Q2TCQ6
ENSG00000133454ENST00000543971H0YGQ4

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
331794332021Further delineation of MYO18B-related autosomal recessive Klippel-Feil syndrome with myopathy and facial dysmorphism.0
335555052021Myosin18B predicts favorable prognosis of cutaneous squamous-cell carcinoma.2
331794332021Further delineation of MYO18B-related autosomal recessive Klippel-Feil syndrome with myopathy and facial dysmorphism.0
335555052021Myosin18B predicts favorable prognosis of cutaneous squamous-cell carcinoma.2
328776722020Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics.6
328776722020Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics.6
305810232019Myosin-18B Promotes the Assembly of Myosin II Stacks for Maturation of Contractile Actomyosin Bundles.20
305810232019Myosin-18B Promotes the Assembly of Myosin II Stacks for Maturation of Contractile Actomyosin Bundles.20
303906772018MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway.10
303906772018MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway.10
281047882017Myo18b is essential for sarcomere assembly in fast skeletal muscle.15
281047882017Myo18b is essential for sarcomere assembly in fast skeletal muscle.15
257484842015A novel syndrome of Klippel-Feil anomaly, myopathy, and characteristic facies is linked to a null mutation in MYO18B.29
257787782015Lack of replication for the myosin-18B association with mathematical ability in independent cohorts.8
257484842015A novel syndrome of Klippel-Feil anomaly, myopathy, and characteristic facies is linked to a null mutation in MYO18B.29

Citation

Dessen P

MYO18B (myosin XVIIIB)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41481/meetings/favicon/js/lib/all.min.js