PADI2 (peptidyl arginine deiminase 2)

2003-05-01  

Identity

HGNC
LOCATION
1p36.13
LOCUSID
ALIAS
PAD-H19,PAD2,PDI2

Other Information

Locus ID:

NCBI: 11240
MIM: 607935
HGNC: 18341
Ensembl: ENSG00000117115

Variants:

dbSNP: 11240
ClinVar: 11240
TCGA: ENSG00000117115
COSMIC: PADI2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117115ENST00000375481Q9Y2J8
ENSG00000117115ENST00000375486Q9Y2J8
ENSG00000117115ENST00000375486A0A024RA98

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378467332024Comparative evaluation of semaphorin-4D, peptidylarginine deiminase-2, and matrix metalloproteinase-8 levels of gingival crevicular fluid in periodontally healthy and Stage III periodontitis smoker and non-smoker patients before and after non-surgical periodontal therapy.0
382532092024PAD2 dysregulation and aberrant protein citrullination feature prominently in reactive astrogliosis and myelin protein aggregation in sporadic ALS.0
382816612024Analysis of the diagnostic and prognostic value of serum PAD2 in patients with sepsis in the intensive care unit.0
378467332024Comparative evaluation of semaphorin-4D, peptidylarginine deiminase-2, and matrix metalloproteinase-8 levels of gingival crevicular fluid in periodontally healthy and Stage III periodontitis smoker and non-smoker patients before and after non-surgical periodontal therapy.0
382532092024PAD2 dysregulation and aberrant protein citrullination feature prominently in reactive astrogliosis and myelin protein aggregation in sporadic ALS.0
382816612024Analysis of the diagnostic and prognostic value of serum PAD2 in patients with sepsis in the intensive care unit.0
377594582023Molecular Factors in PAD2 (PADI2) and PAD4 (PADI4) Are Associated with Interstitial Lung Disease Susceptibility in Rheumatoid Arthritis Patients.2
377594582023Molecular Factors in PAD2 (PADI2) and PAD4 (PADI4) Are Associated with Interstitial Lung Disease Susceptibility in Rheumatoid Arthritis Patients.2
345695422022The Clinical and Prognostic Significance of Protein Arginine Deiminases 2 and 4 in Colorectal Cancer.4
351816882022Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts.4
357373722022Molecular Mechanism of Protein Arginine Deiminase 2: A Study Involving Multiple Microsecond Long Molecular Dynamics Simulations.0
360769332022Peptidylarginine Deiminase 2 Gene Polymorphisms in Subjects with Periodontitis Predispose to Rheumatoid Arthritis.1
345695422022The Clinical and Prognostic Significance of Protein Arginine Deiminases 2 and 4 in Colorectal Cancer.4
351816882022Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts.4
357373722022Molecular Mechanism of Protein Arginine Deiminase 2: A Study Involving Multiple Microsecond Long Molecular Dynamics Simulations.0

Citation

Dessen P

PADI2 (peptidyl arginine deiminase 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41631/deep-insight-explorer/gene-fusions-explorer/js/lib/bootstrap.min.js