RGL2 (ral guanine nucleotide dissociation stimulator like 2)

2003-11-01  

Identity

HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
HKE1.5,KE1.5,RAB2L
FUSION GENES

Other Information

Locus ID:

NCBI: 5863
MIM: 602306
HGNC: 9769
Ensembl: ENSG00000237441

Variants:

dbSNP: 5863
ClinVar: 5863
TCGA: ENSG00000237441
COSMIC: RGL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000237441ENST00000425946A2AB89
ENSG00000237441ENST00000497454O15211
ENSG00000237441ENST00000497454A0A024RCS9

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Ras signaling pathwayKEGGhsa04014

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
208018772010Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms.28
211604982011Functional characterization of SAMD9, a protein deficient in normophosphatemic familial tumoral calcinosis.26
185408612008G-protein binding features and regulation of the RalGDS family member, RGL2.1

Citation

Dessen P

RGL2 (ral guanine nucleotide dissociation stimulator like 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41976/rgl2