RAB33B (RAB33B, member RAS oncogene family)

2003-12-01  

Identity

HGNC
RAB33B
LOCATION
4q31.1
LOCUSID
83452
ALIAS
SMC2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 83452
MIM: 605950
HGNC: 16075
Ensembl: ENSG00000172007

Variants:

dbSNP: 83452
ClinVar: 83452
TCGA: ENSG00000172007
COSMIC: RAB33B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172007ENST00000305626Q9H082
ENSG00000172007ENST00000652268A0A494C0Z5

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Intra-Golgi trafficREACTOMER-HSA-6811438
TBC/RABGAPsREACTOMER-HSA-8854214
RAB geranylgeranylationREACTOMER-HSA-8873719

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
329606762021RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.17
340004392021Seven patients with Smith-McCort dysplasia 2: Four novel nonsense variants in RAB33B and follow-up findings.1
342847422021RAB33B and PCNT variants in two Pakistani families with skeletal dysplasia and short stature.2
329606762021RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.17
340004392021Seven patients with Smith-McCort dysplasia 2: Four novel nonsense variants in RAB33B and follow-up findings.1
342847422021RAB33B and PCNT variants in two Pakistani families with skeletal dysplasia and short stature.2
314089602019Multitasking Rab Proteins in Autophagy and Membrane Trafficking: A Focus on Rab33b.17
314089602019Multitasking Rab Proteins in Autophagy and Membrane Trafficking: A Focus on Rab33b.17
281279402017Additional three patients with Smith-McCort dysplasia due to novel RAB33B mutations.8
286356712017Rab33B Controls Hepatitis B Virus Assembly by Regulating Core Membrane Association and Nucleocapsid Processing.10
281279402017Additional three patients with Smith-McCort dysplasia due to novel RAB33B mutations.8
286356712017Rab33B Controls Hepatitis B Virus Assembly by Regulating Core Membrane Association and Nucleocapsid Processing.10
269754712016Deciphering the role of Atg5 in nucleotide dependent interaction of Rab33B with the dimeric complex, Atg5-Atg16L1.3
273742322016A systematic High-Content Screening microscopy approach reveals key roles for Rab33b, OATL1 and Myo6 in nanoparticle trafficking in HeLa cells.7
269754712016Deciphering the role of Atg5 in nucleotide dependent interaction of Rab33B with the dimeric complex, Atg5-Atg16L1.3

Citation

Dessen P

RAB33B (RAB33B, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41981/js/lib/tumors-explorer/js/_common.js