RAB38 (RAB38, member RAS oncogene family)

2003-05-01  

Identity

HGNC
RAB38
LOCATION
11q14.2
LOCUSID
23682
ALIAS
NY-MEL-1,rrGTPbp
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23682
MIM: 606281
HGNC: 9776
Ensembl: ENSG00000123892

Variants:

dbSNP: 23682
ClinVar: 23682
TCGA: ENSG00000123892
COSMIC: RAB38

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123892ENST00000243662P57729
ENSG00000123892ENST00000243662A0A024R191
ENSG00000123892ENST00000526372H0YDB7
ENSG00000123892ENST00000531138H0YEA4

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198
RAB geranylgeranylationREACTOMER-HSA-8873719

References

Pubmed IDYearTitleCitations
364136032023Evaluation of CRISPR/Cas9 exon-skipping vector for choroideremia using human induced pluripotent stem cell-derived RPE.1
376255892023Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes.3
364136032023Evaluation of CRISPR/Cas9 exon-skipping vector for choroideremia using human induced pluripotent stem cell-derived RPE.1
376255892023Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes.3
342090352021RAB38 Facilitates Energy Metabolism and Counteracts Cell Death in Glioblastoma Cells.1
342090352021RAB38 Facilitates Energy Metabolism and Counteracts Cell Death in Glioblastoma Cells.1
305691142019High expression of RAB38 promotes malignant progression of pancreatic cancer.6
305691142019High expression of RAB38 promotes malignant progression of pancreatic cancer.6
266317372016Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.78
266317372016Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.78
248753592014MiR-124 protects human hepatic L02 cells from H2O2-induced apoptosis by targeting Rab38 gene.10
253245512014Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomes.38
248753592014MiR-124 protects human hepatic L02 cells from H2O2-induced apoptosis by targeting Rab38 gene.10
253245512014Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomes.38
240261992013RAB38 confers a poor prognosis, associated with malignant progression and subtype preference in glioma.14

Citation

Dessen P

RAB38 (RAB38, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41986/case-report-explorer/js/css/card-gene.css