RAB8B (RAB8B, member RAS oncogene family)

2004-02-01  

Identity

HGNC
RAB8B
LOCATION
15q22.2
LOCUSID
51762
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51762
MIM: 613532
HGNC: 30273
Ensembl: ENSG00000166128

Variants:

dbSNP: 51762
ClinVar: 51762
TCGA: ENSG00000166128
COSMIC: RAB8B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166128ENST00000321437Q92930
ENSG00000166128ENST00000558119H0YMN7
ENSG00000166128ENST00000558990H0YLJ8
ENSG00000166128ENST00000559006H0YNE9
ENSG00000166128ENST00000559927H0YL94

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Tight junctionKEGGhsa04530
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198
TBC/RABGAPsREACTOMER-HSA-8854214
RAB geranylgeranylationREACTOMER-HSA-8873719

References

Pubmed IDYearTitleCitations
264717302015Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.62
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
309690722019The rs1986112 Variant is Associated with Increased RAB8B Gene Expression in Schizophrenic Patients.0
317071482019Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer.0

Citation

Dessen P

RAB8B (RAB8B, member RAS oncogene family)

Atlas Genet Cytogenet Oncol Haematol. 2004-02-01

Online version: http://atlasgeneticsoncology.org/gene/42010/rab8b