RARB (retinoic acid receptor beta)

2003-02-01  

Identity

HGNC
LOCATION
3p24.2
LOCUSID
ALIAS
HAP,MCOPS12,NR1B2,RARbeta1,RRB2

Other Information

Locus ID:

NCBI: 5915
MIM: 180220
HGNC: 9865
Ensembl: ENSG00000077092

Variants:

dbSNP: 5915
ClinVar: 5915
TCGA: ENSG00000077092
COSMIC: RARB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000077092ENST00000330688P10826
ENSG00000077092ENST00000330688F1D8S6
ENSG00000077092ENST00000383772D6RBI3
ENSG00000077092ENST00000437042P10826
ENSG00000077092ENST00000437042Q5QHG3
ENSG00000077092ENST00000458646P10826
ENSG00000077092ENST00000458646Q5QHG3

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Small cell lung cancerKEGGko05222
Non-small cell lung cancerKEGGko05223
Pathways in cancerKEGGhsa05200
Small cell lung cancerKEGGhsa05222
Non-small cell lung cancerKEGGhsa05223
Signal TransductionREACTOMER-HSA-162582
Signaling by Retinoic AcidREACTOMER-HSA-5362517
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Nuclear Receptor transcription pathwayREACTOMER-HSA-383280
Developmental BiologyREACTOMER-HSA-1266738
Activation of HOX genes during differentiationREACTOMER-HSA-5619507
Activation of anterior HOX genes in hindbrain development during early embryogenesisREACTOMER-HSA-5617472

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
118348372002Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.164
185198262008Molecular genetics of successful smoking cessation: convergent genome-wide association study results.130
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
146010572003DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma.77
183492822008DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients.71
164787442006Gene promoter methylation in prostate tumor-associated stromal cells.67
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
168586832006Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.55
199022552010Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes.53
199022552010Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes.53

Citation

Dessen P

RARB (retinoic acid receptor beta)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42048/rarb-(retinoic-acid-receptor-beta)