RGS16 (regulator of G protein signaling 16)

2003-11-01  

Identity

HGNC
RGS16
LOCATION
1q25.3
LOCUSID
6004
ALIAS
A28-RGS14,A28-RGS14P,RGS-R

Other Information

Locus ID:

NCBI: 6004
MIM: 602514
HGNC: 9997
Ensembl: ENSG00000143333

Variants:

dbSNP: 6004
ClinVar: 6004
TCGA: ENSG00000143333
COSMIC: RGS16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143333ENST00000367558O15492

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
389068692024Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling.0
389068692024Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling.0
364149162023RGS16 regulated by let-7c-5p promotes glioma progression by activating PI3K-AKT pathway.4
364432502023Gene expression meta-analysis in patients with schizophrenia reveals up-regulation of RGS2 and RGS16 in Brodmann Area 10.1
374735262023RGS16 regulates Hippo-YAP activity to promote esophageal cancer cell proliferation and migration.1
364149162023RGS16 regulated by let-7c-5p promotes glioma progression by activating PI3K-AKT pathway.4
364432502023Gene expression meta-analysis in patients with schizophrenia reveals up-regulation of RGS2 and RGS16 in Brodmann Area 10.1
374735262023RGS16 regulates Hippo-YAP activity to promote esophageal cancer cell proliferation and migration.1
358303662022Critical roles of RGS16 in the mucosal inflammation of ulcerative colitis.2
358303662022Critical roles of RGS16 in the mucosal inflammation of ulcerative colitis.2
323197282020RGS16 promotes glioma progression and serves as a prognostic factor.19
323197282020RGS16 promotes glioma progression and serves as a prognostic factor.19
301171672018The regulators of G protein signaling RGS16 and RGS18 inhibit protease-activated receptor 2/Gi/o signaling through distinct interactions with Gα in live cells.7
301171672018The regulators of G protein signaling RGS16 and RGS18 inhibit protease-activated receptor 2/Gi/o signaling through distinct interactions with Gα in live cells.7
285029232017G-protein-coupled receptor signaling through Gpr176, Gz, and RGS16 tunes time in the center of the circadian clock [Review].8

Citation

Dessen P

RGS16 (regulator of G protein signaling 16)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/42101/css/favicon/favicon-32x32.png