UTP14A (UTP14A small subunit processome component)

2003-06-01  

Identity

HGNC
LOCATION
Xq26.1
LOCUSID
ALIAS
NYCO16,SDCCAG16,Utp14,dJ537K23.3
FUSION GENES

Other Information

Locus ID:

NCBI: 10813
MIM: 300508
HGNC: 10665
Ensembl: ENSG00000156697

Variants:

dbSNP: 10813
ClinVar: 10813
TCGA: ENSG00000156697
COSMIC: UTP14A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000156697ENST00000394422Q9BVJ6
ENSG00000156697ENST00000425117Q9BVJ6
ENSG00000156697ENST00000427972X6RJY0

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Ribosome biogenesis in eukaryotesKEGGko03008
Ribosome biogenesis in eukaryotesKEGGhsa03008
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA modification in the nucleus and cytosolREACTOMER-HSA-6790901
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
210786652011A small ribosomal subunit (SSU) processome component, the human U3 protein 14A (hUTP14A) binds p53 and promotes p53 degradation.15
303431122019Human UTP14a promotes colorectal cancer progression by forming a positive regulation loop with c-Myc.3
282182222017Human U Three Protein 14a Expression is Increased in Hepatocellular Carcinoma and Associated with Poor Prognosis.1
286727762017Human U3 protein 14a plays an anti-apoptotic role in cancer cells.1
307735592019[Expression of hUTP14a in non-small cell lung cancer].0
309299212019Human UTP14a promotes angiogenesis through upregulating PDGFA expression in colorectal cancer.0

Citation

Dessen P

UTP14A (UTP14A small subunit processome component)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42229/utp14a