SLK (STE20 like kinase)

2004-04-01  

Identity

HGNC
LOCATION
10q24.33
LOCUSID
ALIAS
LOSK,STK2,bA16H23.1,se20-9
FUSION GENES

Other Information

Locus ID:

NCBI: 9748
MIM: 616563
HGNC: 11088
Ensembl: ENSG00000065613

Variants:

dbSNP: 9748
ClinVar: 9748
TCGA: ENSG00000065613
COSMIC: SLK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000065613ENST00000335753Q9H2G2
ENSG00000065613ENST00000369755Q9H2G2

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Oocyte meiosisKEGGko04114
Oocyte meiosisKEGGhsa04114

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
319136592020Ste20-like Kinase-mediated Control of Actin Polymerization Is a New Mechanism for Thin Filament-associated Regulation of Airway Smooth Muscle Contraction.13
319136592020Ste20-like Kinase-mediated Control of Actin Polymerization Is a New Mechanism for Thin Filament-associated Regulation of Airway Smooth Muscle Contraction.13
295345782018Ste20-like kinase is upregulated in glioma and induces glioma invasion.2
295345782018Ste20-like kinase is upregulated in glioma and induces glioma invasion.2
260947692015Identification of Tpr and α-actinin-4 as two novel SLK-interacting proteins.3
260947692015Identification of Tpr and α-actinin-4 as two novel SLK-interacting proteins.3
249587722014SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation.44
249587722014SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation.44
239853222013Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome.11
239853222013Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome.11
232093042012Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells.48
232093042012Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells.48
195259802009The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility.22
195259802009The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility.22
182875412008Ste20-related protein kinase LOSK (SLK) controls microtubule radial array in interphase.13

Citation

Dessen P

SLK (STE20 like kinase)

Atlas Genet Cytogenet Oncol Haematol. 2004-04-01

Online version: http://atlasgeneticsoncology.org/gene/42329/tumors-explorer/meetings/favicon/apple-touch-icon.png