ST13 (ST13 Hsp70 interacting protein)

2003-02-01  

Identity

HGNC
ST13
LOCATION
22q13.2
LOCUSID
6767
ALIAS
AAG2,FAM10A1,FAM10A4,HIP,HOP,HSPABP,HSPABP1,P48,PRO0786,SNC6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6767
MIM: 606796
HGNC: 11343
Ensembl: ENSG00000100380

Variants:

dbSNP: 6767
ClinVar: 6767
TCGA: ENSG00000100380
COSMIC: ST13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100380ENST00000216218P50502
ENSG00000100380ENST00000216218A0A140VKA6
ENSG00000100380ENST00000411695F6VDH7
ENSG00000100380ENST00000413424H7C3I1
ENSG00000100380ENST00000455824F8WAQ7
ENSG00000100380ENST00000620312Q3KNR6

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA10832corticosteroidsChemicalClinicalAnnotationassociatedPD25616159
PA443450AsthmaDiseaseClinicalAnnotationassociatedPD25616159

References

Pubmed IDYearTitleCitations
384920992024Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study.0
384920992024Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study.0
327916892020An autophagy-related model of 4 key genes for predicting prognosis of patients with laryngeal cancer.3
327916892020An autophagy-related model of 4 key genes for predicting prognosis of patients with laryngeal cancer.3
256161592015ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.15
256161592015ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.15
231250812012ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines.7
231250812012ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines.7
212406622011Single-point mutation in a conserved TPR domain of Hip disrupts enhancement of glucocorticoid receptor signaling.0
217283852011G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4.23
217676362011Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase.21
212406622011Single-point mutation in a conserved TPR domain of Hip disrupts enhancement of glucocorticoid receptor signaling.0
217283852011G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4.23
217676362011Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase.21
201937432010Expression analysis of suppression of tumorigenicity 13 gene in patients with Parkinson's disease.4

Citation

Dessen P

ST13 (ST13 Hsp70 interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42416/haematological-explorer/gene-fusions-explorer/css/template-nav.css