STARD10 (StAR related lipid transfer domain containing 10)

2003-06-01 Affiliation

Identity

HGNC

STARD10

LOCATION

11q13.4

LOCUSID

10809

ALIAS

CGI-52,NY-CO-28,PCTP2,SDCCAG28

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 10809
MIM: 617382
HGNC: 10666
Ensembl: ENSG00000214530

Variants:

dbSNP: 10809
ClinVar: 10809
TCGA: ENSG00000214530
COSMIC: STARD10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000214530	ENST00000334805	Q9Y365
ENSG00000214530	ENST00000334805	A0A024R5L8
ENSG00000214530	ENST00000400925	H0YGN8
ENSG00000214530	ENST00000535054	F5GY07
ENSG00000214530	ENST00000536290	F5H5A8
ENSG00000214530	ENST00000536377	F5H3G8
ENSG00000214530	ENST00000536728	H0YGA9
ENSG00000214530	ENST00000537351	H0YH17
ENSG00000214530	ENST00000537947	F5H1Z6
ENSG00000214530	ENST00000538536	F5GY11
ENSG00000214530	ENST00000539138	F5GWK5
ENSG00000214530	ENST00000540587	F5GY42
ENSG00000214530	ENST00000542989	F5H8G1
ENSG00000214530	ENST00000543304	Q9Y365
ENSG00000214530	ENST00000543304	A0A024R5L8
ENSG00000214530	ENST00000544767	H0YFF3
ENSG00000214530	ENST00000545082	F5H8H3
ENSG00000214530	ENST00000546314	F5H0V7

Expression (GTEx)

100

150

200

250

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism	REACTOME	R-HSA-1430728
Metabolism of lipids and lipoproteins	REACTOME	R-HSA-556833
Phospholipid metabolism	REACTOME	R-HSA-1483257
Glycerophospholipid biosynthesis	REACTOME	R-HSA-1483206
Synthesis of PC	REACTOME	R-HSA-1483191

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	85
14576202	2003	Transcriptional profiling of the heart reveals chamber-specific gene expression patterns.	28
15911624	2005	StarD10, a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein.	28
28132686	2017	Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.	13
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	11
17561512	2007	Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity.	4
19676041	2010	Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.	4
28412359	2017	Potentiation of docetaxel sensitivity by miR-638 via regulation of STARD10 pathway in human breast cancer cells.	4
30611309	2019	Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression.	0

Citation

Dessen P

STARD10 (StAR related lipid transfer domain containing 10)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42428/stard10