TBRG4 (transforming growth factor beta regulator 4)

2003-11-01  

Identity

HGNC
TBRG4
LOCATION
7p13
LOCUSID
9238
ALIAS
CPR2,FASTKD4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9238
MIM: 611325
HGNC: 17443
Ensembl: ENSG00000136270

Variants:

dbSNP: 9238
ClinVar: 9238
TCGA: ENSG00000136270
COSMIC: TBRG4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136270ENST00000258770Q969Z0
ENSG00000136270ENST00000361278Q969Z0
ENSG00000136270ENST00000395655Q969Z0
ENSG00000136270ENST00000461363C9J7P5
ENSG00000136270ENST00000475893C9J347
ENSG00000136270ENST00000478532C9IZN7
ENSG00000136270ENST00000482285C9J5A2
ENSG00000136270ENST00000483615H7C4R5
ENSG00000136270ENST00000494076Q969Z0
ENSG00000136270ENST00000495078C9J618

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383474892024High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.0
383474892024High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.0
364174782022Mitochondrial protein, TBRG4, modulates KSHV and EBV reactivation from latency.0
364174782022Mitochondrial protein, TBRG4, modulates KSHV and EBV reactivation from latency.0
336755382021Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients.3
347485622021The FASTK family proteins fine-tune mitochondrial RNA processing.9
336755382021Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients.3
347485622021The FASTK family proteins fine-tune mitochondrial RNA processing.9
324159432020TBRG4 silencing promotes progression of squamous cell carcinoma via regulation of CAV-1 expression and ROS formation.5
324159432020TBRG4 silencing promotes progression of squamous cell carcinoma via regulation of CAV-1 expression and ROS formation.5
283350012017FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain.29
284758952017SLERT Regulates DDX21 Rings Associated with Pol I Transcription.117
290363962017The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.41
283350012017FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain.29
284758952017SLERT Regulates DDX21 Rings Associated with Pol I Transcription.117

Citation

Dessen P

TBRG4 (transforming growth factor beta regulator 4)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/42483/img/css/lib/bootstrap.min.css