TRIM29 (tripartite motif containing 29)

2003-06-01  

Identity

HGNC
TRIM29
LOCATION
11q23.3
LOCUSID
23650
ALIAS
ATDC
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23650
MIM: 610658
HGNC: 17274
Ensembl: ENSG00000137699

Variants:

dbSNP: 23650
ClinVar: 23650
TCGA: ENSG00000137699
COSMIC: TRIM29

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137699ENST00000341846Q14134
ENSG00000137699ENST00000341846A0A024R3J1
ENSG00000137699ENST00000475051E9PJD4
ENSG00000137699ENST00000526881E9PPX1
ENSG00000137699ENST00000528870E9PIQ2
ENSG00000137699ENST00000529011E9PJ94
ENSG00000137699ENST00000529040E9PM74
ENSG00000137699ENST00000529044E9PRL4
ENSG00000137699ENST00000529495E9PLI4
ENSG00000137699ENST00000531555H0YD78
ENSG00000137699ENST00000532833E9PI31
ENSG00000137699ENST00000533302H0YF27
ENSG00000137699ENST00000627238E9PJD4

Expression (GTEx)

0
100
200
300
400
500
600
700
800
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
192496792009Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization.83
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
203683522010The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions.36
290384222017TRIM29 promotes DNA virus infections by inhibiting innate immune response.36
194304192009A novel five-antibody immunohistochemical test for subclassification of lung carcinoma.34
232011302013Multicenter validation of cyclin D1, MCM7, TRIM29, and UBE2C as prognostic protein markers in non-muscle-invasive bladder cancer.28
200832282010Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India.27
214636572011TRIM29 negatively regulates p53 via inhibition of Tip60.25
209475012010Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein.23
268723692016Upregulated TRIM29 promotes proliferation and metastasis of nasopharyngeal carcinoma via PTEN/AKT/mTOR signal pathway.22

Citation

Dessen P

TRIM29 (tripartite motif containing 29)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42701/trim29