WNT10A (Wnt family member 10A)

2003-02-01  

Identity

HGNC
WNT10A
LOCATION
2q35
LOCUSID
80326
ALIAS
OODD,SSPS,STHAG4

Other Information

Locus ID:

NCBI: 80326
MIM: 606268
HGNC: 13829
Ensembl: ENSG00000135925

Variants:

dbSNP: 80326
ClinVar: 80326
TCGA: ENSG00000135925
COSMIC: WNT10A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135925ENST00000258411Q9GZT5
ENSG00000135925ENST00000258411A0A2K8FR47
ENSG00000135925ENST00000458582H7BZB8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
Wnt signaling pathwayKEGGko04310
MelanogenesisKEGGko04916
Basal cell carcinomaKEGGko05217
mTOR signaling pathwayKEGGhsa04150
Wnt signaling pathwayKEGGhsa04310
MelanogenesisKEGGhsa04916
Pathways in cancerKEGGhsa05200
Basal cell carcinomaKEGGhsa05217
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Proteoglycans in cancerKEGGhsa05205
Proteoglycans in cancerKEGGko05205
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Wnt signalingKEGGhsa_M00677
Wnt signalingKEGGM00677
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Signaling by WntREACTOMER-HSA-195721
WNT ligand biogenesis and traffickingREACTOMER-HSA-3238698
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
382731782024SENP3 Promotes Mantle Cell Lymphoma Development through Regulating Wnt10a Expression.0
382809922024Compound heterozygous WNT10A missense variations exacerbated the tooth agenesis caused by hypohidrotic ectodermal dysplasia.0
382731782024SENP3 Promotes Mantle Cell Lymphoma Development through Regulating Wnt10a Expression.0
382809922024Compound heterozygous WNT10A missense variations exacerbated the tooth agenesis caused by hypohidrotic ectodermal dysplasia.0
355378902023Novel Dental Anomaly-associated Mutations in WNT10A Protein Binding Sites.4
374229972023Phenotypic characteristics of taurodontism and a novel WNT10A variant in non-syndromic oligodontia family.0
375666202023The investigation of WNT6 and WNT10A single nucleotide polymorphisms as potential biomarkers for dental pulp calcification in orthodontic patients.2
376716652023Short anagen hair syndrome: association with mono- and biallelic variants in WNT10A and a genetic overlap with male pattern hair loss.0
355378902023Novel Dental Anomaly-associated Mutations in WNT10A Protein Binding Sites.4
374229972023Phenotypic characteristics of taurodontism and a novel WNT10A variant in non-syndromic oligodontia family.0
375666202023The investigation of WNT6 and WNT10A single nucleotide polymorphisms as potential biomarkers for dental pulp calcification in orthodontic patients.2
376716652023Short anagen hair syndrome: association with mono- and biallelic variants in WNT10A and a genetic overlap with male pattern hair loss.0
359993852022WNT10A variants: following the pattern of inheritance in tooth agenesis and self-reported family history of cancer.2
359993852022WNT10A variants: following the pattern of inheritance in tooth agenesis and self-reported family history of cancer.2
330342462021Functional Effects of WNT10A Rare Variants Associated with Tooth Agenesis.13

Citation

Dessen P

WNT10A (Wnt family member 10A)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42816/js/lib/jquery-3.5.1.min.js