MYO18A (myosin XVIIIA)

2004-08-01  

Identity

HGNC
MYO18A
LOCATION
17q11.2
LOCUSID
399687
ALIAS
MAJN,MYSPDZ,SP-R210,SPR210
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 399687
MIM: 610067
HGNC: 31104
Ensembl: ENSG00000196535

Variants:

dbSNP: 399687
ClinVar: 399687
TCGA: ENSG00000196535
COSMIC: MYO18A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196535ENST00000527372Q92614
ENSG00000196535ENST00000528564H0YEV9
ENSG00000196535ENST00000530254E9PN42
ENSG00000196535ENST00000531253Q92614
ENSG00000196535ENST00000531253A0A024QZ63
ENSG00000196535ENST00000533112Q92614
ENSG00000196535ENST00000533420A0A1B0GWJ6
ENSG00000196535ENST00000588791K7EKB3
ENSG00000196535ENST00000628822A0A0D9SFK2
ENSG00000196535ENST00000636100A0A1B0GV45

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
DiseaseREACTOMER-HSA-1643685
Diseases of signal transductionREACTOMER-HSA-5663202
Signaling by FGFR in diseaseREACTOMER-HSA-1226099
Signaling by FGFR1 in diseaseREACTOMER-HSA-5655302
FGFR1 mutant receptor activationREACTOMER-HSA-1839124
Signaling by cytosolic FGFR1 fusion mutantsREACTOMER-HSA-1839117

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381350242024SP-R210 isoforms of Myosin18A modulate endosomal sorting and recognition of influenza A virus infection in macrophages.0
381350242024SP-R210 isoforms of Myosin18A modulate endosomal sorting and recognition of influenza A virus infection in macrophages.0
289423522018MYO18A: An unusual myosin.19
289423522018MYO18A: An unusual myosin.19
275287482016How myosin organization of the actin cytoskeleton contributes to the cancer phenotype.19
275287482016How myosin organization of the actin cytoskeleton contributes to the cancer phenotype.19
244854522014DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3.117
244854522014DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3.117
233455922013GOLPH3L antagonizes GOLPH3 to determine Golgi morphology.38
239904652013Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.33
233455922013GOLPH3L antagonizes GOLPH3 to determine Golgi morphology.38
239904652013Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.33
225348282012TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death.26
225348282012TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death.26
217518082011Proteomics analysis of the ezrin interactome in B cells reveals a novel association with Myo18aα.8

Citation

Dessen P

MYO18A (myosin XVIIIA)

Atlas Genet Cytogenet Oncol Haematol. 2004-08-01

Online version: http://atlasgeneticsoncology.org/gene/42921/js/lib/js/css/card-gene.css