DPP9 (dipeptidyl peptidase 9)

2004-11-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
DP9,DPLP9,DPP
FUSION GENES

Other Information

Locus ID:

NCBI: 91039
MIM: 608258
HGNC: 18648
Ensembl: ENSG00000142002

Variants:

dbSNP: 91039
ClinVar: 91039
TCGA: ENSG00000142002
COSMIC: DPP9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000142002ENST00000262960Q86TI2
ENSG00000142002ENST00000593973M0QXN4
ENSG00000142002ENST00000594671Q86TI2
ENSG00000142002ENST00000595327M0R1L4
ENSG00000142002ENST00000597726M0R3E8
ENSG00000142002ENST00000597849M0R2A8
ENSG00000142002ENST00000597900M0R334
ENSG00000142002ENST00000598041M0QXG6
ENSG00000142002ENST00000598360M0R0I1
ENSG00000142002ENST00000598800Q86TI2
ENSG00000142002ENST00000599163M0R162
ENSG00000142002ENST00000599248M0QXA6
ENSG00000142002ENST00000600556M0QZ97
ENSG00000142002ENST00000600621M0R2G6
ENSG00000142002ENST00000601130M0R145
ENSG00000142002ENST00000601720M0QXI5
ENSG00000142002ENST00000602161M0R3C4
ENSG00000142002ENST00000646573A0A2R8YF65

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
236087732013Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.22
152459132004Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity.21
302911412018Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.19
196670702009The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides.18
235194732013Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism.18
195816302009The in vivo expression of dipeptidyl peptidases 8 and 9.16
167044182006Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis.15
216226242011A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling.15
231525012012A novel SUMO1-specific interacting motif in dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation.13
217110532011Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?12

Citation

Dessen P

DPP9 (dipeptidyl peptidase 9)

Atlas Genet Cytogenet Oncol Haematol. 2004-11-01

Online version: http://atlasgeneticsoncology.org/gene/42928/dpp9-(dipeptidyl-peptidase-9)