TUSC1 (tumor suppressor candidate 1)

2004-11-01  

Identity

HGNC
LOCATION
9p21.2
LOCUSID
ALIAS
CCDC89B,TSG-9,TSG9

Other Information

Locus ID:

NCBI: 286319
MIM: 610529
HGNC: 31010
Ensembl: ENSG00000198680

Variants:

dbSNP: 286319
ClinVar: 286319
TCGA: ENSG00000198680
COSMIC: TUSC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198680ENST00000358022Q2TAM9

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
354348542022Circular RNA circ_0065378 upregulates tumor suppressor candidate 1 by competitively binding with miR-4701-5p to alleviate colorectal cancer progression.7
354348542022Circular RNA circ_0065378 upregulates tumor suppressor candidate 1 by competitively binding with miR-4701-5p to alleviate colorectal cancer progression.7
289754882018Association of TUSC1 and DPF3 gene polymorphisms with male infertility.9
289754882018Association of TUSC1 and DPF3 gene polymorphisms with male infertility.9
268973572017Tumor Suppressor Candidate 1 Suppresses Cell Growth and Predicts Better Survival in Glioblastoma.7
268973572017Tumor Suppressor Candidate 1 Suppresses Cell Growth and Predicts Better Survival in Glioblastoma.7
243660002014Identification of intragenic methylation in the TUSC1 gene as a novel prognostic marker of hepatocellular carcinoma.11
247004962014Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer.14
243660002014Identification of intragenic methylation in the TUSC1 gene as a novel prognostic marker of hepatocellular carcinoma.11
247004962014Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer.14
237766182013TUSC1, a putative tumor suppressor gene, reduces tumor cell growth in vitro and tumor growth in vivo.19
237766182013TUSC1, a putative tumor suppressor gene, reduces tumor cell growth in vitro and tumor growth in vivo.19
205748432010Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.21
205748432010Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.21
152086652004Identifying novel homozygous deletions by microsatellite analysis and characterization of tumor suppressor candidate 1 gene, TUSC1, on chromosome 9p in human lung cancer.13

Citation

Dessen P

TUSC1 (tumor suppressor candidate 1)

Atlas Genet Cytogenet Oncol Haematol. 2004-11-01

Online version: http://atlasgeneticsoncology.org/gene/42955/gene-fusions-explorer/favicon/apple-touch-icon.png