USP42 (ubiquitin specific peptidase 42)

2007-03-01  

Identity

HGNC
LOCATION
7p22.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 84132
HGNC: 20068
Ensembl: ENSG00000106346

Variants:

dbSNP: 84132
ClinVar: 84132
TCGA: ENSG00000106346
COSMIC: USP42

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106346ENST00000306177Q9H9J4
ENSG00000106346ENST00000404008B4DP25
ENSG00000106346ENST00000426246C9JPC9
ENSG00000106346ENST00000451154F8WD92
ENSG00000106346ENST00000465073E7EWZ4
ENSG00000106346ENST00000521713E5RJP3

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DeubiquitinationREACTOMER-HSA-5688426
Ub-specific processing proteasesREACTOMER-HSA-5689880

References

Pubmed IDYearTitleCitations
220859282011Regulation of p53 stability and function by the deubiquitinating enzyme USP42.39
253366402014Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity.17
246736272014Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del(5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts.4
270309892016Overexpression and Biological Function of Ubiquitin-Specific Protease 42 in Gastric Cancer.4

Citation

Dessen P

USP42 (ubiquitin specific peptidase 42)

Atlas Genet Cytogenet Oncol Haematol. 2007-03-01

Online version: http://atlasgeneticsoncology.org/gene/42965/usp42-(ubiquitin-specific-peptidase-42)