TRPS1 (transcriptional repressor GATA binding 1)

2003-05-01  

Identity

HGNC
TRPS1
LOCATION
8q23.3
LOCUSID
7227
ALIAS
GC79,LGCR
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7227
MIM: 604386
HGNC: 12340
Ensembl: ENSG00000104447

Variants:

dbSNP: 7227
ClinVar: 7227
TCGA: ENSG00000104447
COSMIC: TRPS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104447ENST00000220888Q9UHF7
ENSG00000104447ENST00000395713F8W8T0
ENSG00000104447ENST00000395715Q9UHF7
ENSG00000104447ENST00000422939C9J6L7
ENSG00000104447ENST00000451156A0A1D5RMP4
ENSG00000104447ENST00000517323H0YC29
ENSG00000104447ENST00000518018H0YAV4
ENSG00000104447ENST00000519076E5RFF3
ENSG00000104447ENST00000519674E5RJ97
ENSG00000104447ENST00000519815E7EVN4
ENSG00000104447ENST00000520276Q9UHF7
ENSG00000104447ENST00000640765Q9UHF7

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
216733162011TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer.95
160437162005The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer.94
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
218683602011miR-221/222 targeting of trichorhinophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer.44
126202332003Selective dimerization of a C2H2 zinc finger subfamily.34
187137542008A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice.23
252771972014A central role for TRPS1 in the control of cell cycle and cancer development.21
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
257925222015Phenotype and genotype in 103 patients with tricho-rhino-phalangeal syndrome.18

Citation

Dessen P

TRPS1 (transcriptional repressor GATA binding 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/430/trps1-(transcriptional-repressor-gata-binding-1)