ARF4 (ADP ribosylation factor 4)

2006-10-01  

Identity

HGNC
ARF4
LOCATION
3p14.3
LOCUSID
378
ALIAS
ARF2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 378
MIM: 601177
HGNC: 655
Ensembl: ENSG00000168374

Variants:

dbSNP: 378
ClinVar: 378
TCGA: ENSG00000168374
COSMIC: ARF4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168374ENST00000303436P18085
ENSG00000168374ENST00000463880C9JPM4
ENSG00000168374ENST00000486310F8WDB3
ENSG00000168374ENST00000488156C9J6P1
ENSG00000168374ENST00000489843U3KQF2
ENSG00000168374ENST00000496292C9JAK5

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Cargo trafficking to the periciliary membraneREACTOMER-HSA-5620920
VxPx cargo-targeting to ciliumREACTOMER-HSA-5620916
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

References

Pubmed IDYearTitleCitations
310680622021The ins and outs of the Arf4-based ciliary membrane-targeting complex.12
334161782021microRNA‑196a‑3p inhibits cell proliferation and promotes cell apoptosis by targeting ADP ribosylation factor 4 in diffuse large B‑cell lymphoma.3
335616102021Quantitative Proteomics Reveals Association of Neuron Projection Development Genes ARF4, KIF5B, and RAB8A With Hirschsprung Disease.5
310680622021The ins and outs of the Arf4-based ciliary membrane-targeting complex.12
334161782021microRNA‑196a‑3p inhibits cell proliferation and promotes cell apoptosis by targeting ADP ribosylation factor 4 in diffuse large B‑cell lymphoma.3
335616102021Quantitative Proteomics Reveals Association of Neuron Projection Development Genes ARF4, KIF5B, and RAB8A With Hirschsprung Disease.5
316728442020Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake.23
328283032020Class II Arfs require a brefeldin-A-sensitive factor for Golgi association.2
316728442020Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake.23
328283032020Class II Arfs require a brefeldin-A-sensitive factor for Golgi association.2
280574862018MiR-221-3p targets ARF4 and inhibits the proliferation and migration of epithelial ovarian cancer cells.30
280574862018MiR-221-3p targets ARF4 and inhibits the proliferation and migration of epithelial ovarian cancer cells.30
287608262017Commensal microbiota-induced microRNA modulates intestinal epithelial permeability through the small GTPase ARF4.0
288405652017Interplay between hepatitis C virus and ARF4.2
287608262017Commensal microbiota-induced microRNA modulates intestinal epithelial permeability through the small GTPase ARF4.0

Citation

Dessen P

ARF4 (ADP ribosylation factor 4)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43125/css/lib/tumors-explorer/favicon/favicon-16x16.png