ARHGAP10 (Rho GTPase activating protein 10)

2006-10-01  

Identity

HGNC
LOCATION
4q31.23
LOCUSID
ALIAS
GRAF2,PS-GAP,PSGAP
FUSION GENES

Other Information

Locus ID:

NCBI: 79658
MIM: 609746
HGNC: 26099
Ensembl: ENSG00000071205

Variants:

dbSNP: 79658
ClinVar: 79658
TCGA: ENSG00000071205
COSMIC: ARHGAP10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000071205ENST00000336498A1A4S6
ENSG00000071205ENST00000336498A0A2X0SFB3
ENSG00000071205ENST00000507661H0Y8W5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Bacterial invasion of epithelial cellsKEGGko05100
Bacterial invasion of epithelial cellsKEGGhsa05100
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840
Programmed Cell DeathREACTOMER-HSA-5357801
ApoptosisREACTOMER-HSA-109581
Regulation of ApoptosisREACTOMER-HSA-169911
Regulation of PAK-2p34 activity by PS-GAP/RHG10REACTOMER-HSA-211728

References

Pubmed IDYearTitleCitations
317894192020miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10.13
323444332020GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.17
326992482020ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk.24
317894192020miR‑337‑3p inhibits gastric tumor metastasis by targeting ARHGAP10.13
323444332020GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.17
326992482020ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk.24
314457072019CXCL12 promotes human ovarian cancer cell invasion through suppressing ARHGAP10 expression.8
314457072019CXCL12 promotes human ovarian cancer cell invasion through suppressing ARHGAP10 expression.8
270108582016ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells.38
270108582016ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells.38
199110112010Mutation of ARHGAP9 in patients with coronary spastic angina.0
201583042010A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.55
203322632010A genome-wide association study of prognosis in breast cancer.46
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
199110112010Mutation of ARHGAP9 in patients with coronary spastic angina.0

Citation

Dessen P

ARHGAP10 (Rho GTPase activating protein 10)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43130/favicon/tumors-explorer/css/lib/dataTables.bootstrap.min.css