BAG5 (BAG cochaperone 5)

2006-10-01  

Identity

HGNC
BAG5
LOCATION
14q32.33
LOCUSID
9529
ALIAS
BAG-5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9529
MIM: 603885
HGNC: 941
Ensembl: ENSG00000166170

Variants:

dbSNP: 9529
ClinVar: 9529
TCGA: ENSG00000166170
COSMIC: BAG5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166170ENST00000299204Q9UL15
ENSG00000166170ENST00000299204A0A024R6M6
ENSG00000166170ENST00000337322Q9UL15
ENSG00000166170ENST00000445922Q9UL15
ENSG00000166170ENST00000445922A0A024R6M6
ENSG00000166170ENST00000557666G3V274

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
245109042014Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.136
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
156037372004BAG5 inhibits parkin and enhances dopaminergic neuron degeneration.59
213588152011Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5).48
234486672013Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis.23
208197782010MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.21
244750982014BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation.20
208555362010Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma.18
208555362010Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma.18
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.17

Citation

Dessen P

BAG5 (BAG cochaperone 5)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43161/bag5-(bag-cochaperone-5)