CARD16 (caspase recruitment domain family member 16)

2006-10-01  

Identity

HGNC
LOCATION
11q22.3
LOCUSID
ALIAS
COP,COP1,LLID-114769,PSEUDO-ICE

Other Information

Locus ID:

NCBI: 114769
MIM: 615680
HGNC: 33701
Ensembl: ENSG00000204397

Variants:

dbSNP: 114769
ClinVar: 114769
TCGA: ENSG00000204397
COSMIC: CARD16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204397ENST00000375704Q5EG05
ENSG00000204397ENST00000375706Q5EG05

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
NOD-like receptor signaling pathwayKEGGko04621
NOD-like receptor signaling pathwayKEGGhsa04621

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
163549232005Dysregulation of receptor interacting protein-2 and caspase recruitment domain only protein mediates aberrant caspase-1 activation in Huntington's disease.11
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
265217432015IL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22(phox) and NOX4 activity in human articular chondrocytes.11
169203342006Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death.8

Citation

Dessen P

CARD16 (caspase recruitment domain family member 16)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43217/card16-(caspase-recruitment-domain-family-member-16)