EPHA6 (EPH receptor A6)

2006-10-01  

Identity

HGNC
LOCATION
3q11.2
LOCUSID
ALIAS
EHK-2,EHK2,EK12,EPA6,HEK12,PRO57066
FUSION GENES

Other Information

Locus ID:

NCBI: 285220
MIM: 600066
HGNC: 19296
Ensembl: ENSG00000080224

Variants:

dbSNP: 285220
ClinVar: 285220
TCGA: ENSG00000080224
COSMIC: EPHA6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000080224ENST00000389672A0A0B4J1T8
ENSG00000080224ENST00000470610E7EU71
ENSG00000080224ENST00000477384J3KR66
ENSG00000080224ENST00000502694Q9UF33
ENSG00000080224ENST00000503760B4DXM2
ENSG00000080224ENST00000506349H0Y8K5
ENSG00000080224ENST00000506569H0Y9V0
ENSG00000080224ENST00000508345B4DXQ6
ENSG00000080224ENST00000514100Q9UF33

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Axon guidanceKEGGhsa04360
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
EPH-Ephrin signalingREACTOMER-HSA-2682334
EPHA-mediated growth cone collapseREACTOMER-HSA-3928663
EPH-ephrin mediated repulsion of cellsREACTOMER-HSA-3928665

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
255834932015Novel recurrently mutated genes in African American colon cancers.42
209507862010A genome-wide study reveals copy number variants exclusive to childhood obesity cases.41
198502832010Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.27
275824842017Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.5
200110782009Gradients of Eph-A6 expression in primate retina suggest roles in both vascular and axon guidance.0
260418872015EphA6 promotes angiogenesis and prostate cancer metastasis and is associated with human prostate cancer progression.0
292080022017EPHA6 rs4857055 C > T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population.0
314839182019Tyrosine kinase Eph receptor A6 sensitizes glioma-initiating cells towards bone morphogenetic protein-induced apoptosis.0

Citation

Dessen P

EPHA6 (EPH receptor A6)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43244/epha6-(eph-receptor-a6)