FAF1 (Fas associated factor 1)

2006-10-01  

Identity

HGNC
LOCATION
1p32.3
LOCUSID
ALIAS
CGI-03,HFAF1s,UBXD12,UBXN3A,hFAF1
FUSION GENES

Other Information

Locus ID:

NCBI: 11124
MIM: 604460
HGNC: 3578
Ensembl: ENSG00000185104

Variants:

dbSNP: 11124
ClinVar: 11124
TCGA: ENSG00000185104
COSMIC: FAF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185104ENST00000371778B1ANM7
ENSG00000185104ENST00000396153Q9UNN5
ENSG00000185104ENST00000494400B3KT28

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
201955462010miR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cells.86
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
191747802009Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.52
157438422005Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway.42
216458542011Hierarchical binding of cofactors to the AAA ATPase p97.40
146001572004Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB.35
194229352009Genetic risk profiling and prediction of disease course in Crohn's disease patients.33
127027232003Fas-associated factor 1, FAF1, is a member of Fas death-inducing signaling complex.31
219786682011The NLRP12 pyrin domain: structure, dynamics, and functional insights.28

Citation

Dessen P

FAF1 (Fas associated factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43250/faf1-(fas-associated-factor-1)