FAF1 (Fas associated factor 1)

2006-10-01  

Identity

HGNC
FAF1
LOCATION
1p32.3
LOCUSID
11124
ALIAS
CGI-03,HFAF1s,UBXD12,UBXN3A,hFAF1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11124
MIM: 604460
HGNC: 3578
Ensembl: ENSG00000185104

Variants:

dbSNP: 11124
ClinVar: 11124
TCGA: ENSG00000185104
COSMIC: FAF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185104ENST00000371778B1ANM7
ENSG00000185104ENST00000396153Q9UNN5
ENSG00000185104ENST00000494400B3KT28

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
342554212022Association analysis of SNPs in GRHL3, FAF1, and KCNJ2 with NSCPO sub-phenotypes in Han Chinese.0
342554212022Association analysis of SNPs in GRHL3, FAF1, and KCNJ2 with NSCPO sub-phenotypes in Han Chinese.0
344645092021FAF1 downregulation by Toxoplasma gondii enables host IRF3 mobilization and promotes parasite growth.6
346445762021USP7 and VCP(FAF1) define the SUMO/Ubiquitin landscape at the DNA replication fork.10
344645092021FAF1 downregulation by Toxoplasma gondii enables host IRF3 mobilization and promotes parasite growth.6
346445762021USP7 and VCP(FAF1) define the SUMO/Ubiquitin landscape at the DNA replication fork.10
321790922020Germline Mutations in FAF1 Are Associated With Hereditary Colorectal Cancer.15
328310992020A novel function of FAF1, which induces dopaminergic neuronal death through cell-to-cell transmission.7
321790922020Germline Mutations in FAF1 Are Associated With Hereditary Colorectal Cancer.15
328310992020A novel function of FAF1, which induces dopaminergic neuronal death through cell-to-cell transmission.7
309153562019C(18)H(17)NO(6) and Its Combination with Scutellarin Suppress the Proliferation and Induce the Apoptosis of Human Glioma Cells via Upregulation of Fas-Associated Factor 1 Expression.7
309359672019Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation.7
309153562019C(18)H(17)NO(6) and Its Combination with Scutellarin Suppress the Proliferation and Induce the Apoptosis of Human Glioma Cells via Upregulation of Fas-Associated Factor 1 Expression.7
309359672019Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation.7
292572702018Long non‑coding RNA FAF1 promotes intervertebral disc degeneration by targeting the Erk signaling pathway.16

Citation

Dessen P

FAF1 (Fas associated factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43250/meetings/favicon/js/css/template-nav.css