ARHGEF40 (Rho guanine nucleotide exchange factor 40)

2006-10-01  

Identity

HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
SOLO
FUSION GENES

Other Information

Locus ID:

NCBI: 55701
MIM: 610018
HGNC: 25516
Ensembl: ENSG00000165801

Variants:

dbSNP: 55701
ClinVar: 55701
TCGA: ENSG00000165801
COSMIC: ARHGEF40

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165801ENST00000298694Q8TER5
ENSG00000165801ENST00000553709G3V5C1
ENSG00000165801ENST00000555038G3V3N2
ENSG00000165801ENST00000556399G3V485

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signalling by NGFREACTOMER-HSA-166520
p75 NTR receptor-mediated signallingREACTOMER-HSA-193704
Cell death signalling via NRAGE, NRIF and NADEREACTOMER-HSA-204998
NRAGE signals death through JNKREACTOMER-HSA-193648
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (12/13) signalling eventsREACTOMER-HSA-416482

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
161434672005Identification, expression analysis, genomic organization and cellular location of a novel protein with a RhoGEF domain.6
309293002019Keratin-binding ability of the N-terminal Solo domain of Solo is critical for its function in cellular mechanotransduction.1

Citation

Dessen P

ARHGEF40 (Rho guanine nucleotide exchange factor 40)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43264/arhgef40-(rho-guanine-nucleotide-exchange-factor-40)