CILK1 (ciliogenesis associated kinase 1)

2006-10-01 Affiliation

HGNC

CILK1

LOCATION

6p12.1

LOCUSID

22858

ALIAS

ECO,EJM10,ICK,LCK2,MRK,hICK

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

dbSNP: 22858
ClinVar: 22858
TCGA: ENSG00000112144
COSMIC: CILK1

Pubmed ID	Year	Title	Citations
19240061	2009	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	75
23743448	2013	CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner.	35
16954377	2006	Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase.	33
15988018	2005	Activation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase.	27
22761715	2012	Identification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen.	27
19185282	2009	A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems.	25
19696144	2009	Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells.	22
19696144	2009	Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells.	22
22356909	2012	Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.	15
27466187	2016	An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.	12

Dessen P

CILK1 (ciliogenesis associated kinase 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01