CIAPIN1 (cytokine induced apoptosis inhibitor 1)

2007-02-01  

Identity

HGNC
LOCATION
16q21
LOCUSID
ALIAS
Anamorsin,CIAE2,DRE2,PRO0915
FUSION GENES

Other Information

Locus ID:

NCBI: 57019
MIM: 608943
HGNC: 28050
Ensembl: ENSG00000005194

Variants:

dbSNP: 57019
ClinVar: 57019
TCGA: ENSG00000005194
COSMIC: CIAPIN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000005194ENST00000394391Q6FI81
ENSG00000005194ENST00000563341H3BQ23
ENSG00000005194ENST00000565786H3BTT4
ENSG00000005194ENST00000565961H3BPG7
ENSG00000005194ENST00000567518Q6FI81
ENSG00000005194ENST00000567751H3BTZ8
ENSG00000005194ENST00000568940H3BT65
ENSG00000005194ENST00000569370H3BT65
ENSG00000005194ENST00000569979H3BV90
ENSG00000005194ENST00000570000H3BUG4

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Cytosolic iron-sulfur cluster assemblyREACTOMER-HSA-2564830

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
217002142011Anamorsin is a [2Fe-2S] cluster-containing substrate of the Mia40-dependent mitochondrial protein trapping machinery.23
235962122013Molecular view of an electron transfer process essential for iron-sulfur protein biogenesis.16
164107212006CIAPIN1 confers multidrug resistance by upregulating the expression of MDR-1 and MRP-1 in gastric cancer cells.13
182992782008Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo.13
258896872015CIAPIN1 and ABCA13 are markers of poor survival in metastatic ovarian serous carcinoma.13
190811792009CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma.12
182934922007CIAPIN1 inhibits gastric cancer cell proliferation and cell cycle progression by downregulating CyclinD1 and upregulating P27.9
239894062013Human anamorsin binds [2Fe-2S] clusters with unique electronic properties.9
208159022010Expression of CIAPIN1 in human colorectal cancer and its correlation with prognosis.8
180595322007A new apoptosis inhibitor, CIAPIN1 (cytokine-induced apoptosis inhibitor 1), mediates multidrug resistance in leukemia cells by regulating MDR-1, Bcl-2, and Bax.7

Citation

Dessen P

CIAPIN1 (cytokine induced apoptosis inhibitor 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43585/ciapin1-(cytokine-induced-apoptosis-inhibitor-1)