HNRNPF (heterogeneous nuclear ribonucleoprotein F)

2007-02-01  

Identity

HGNC
HNRNPF
LOCATION
10q11.21
LOCUSID
3185
ALIAS
HNRPF,OK/SW-cl.23,mcs94-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3185
MIM: 601037
HGNC: 5039
Ensembl: ENSG00000169813

Variants:

dbSNP: 3185
ClinVar: 3185
TCGA: ENSG00000169813
COSMIC: HNRNPF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169813ENST00000337970P52597
ENSG00000169813ENST00000337970A0A024R7T3
ENSG00000169813ENST00000356053P52597
ENSG00000169813ENST00000356053A0A024R7T3
ENSG00000169813ENST00000357065P52597
ENSG00000169813ENST00000357065A0A024R7T3
ENSG00000169813ENST00000443950P52597
ENSG00000169813ENST00000443950A0A024R7T3
ENSG00000169813ENST00000477108A0A1B0GW42
ENSG00000169813ENST00000544000P52597
ENSG00000169813ENST00000544000A0A024R7T3

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by FGFRREACTOMER-HSA-190236
Signaling by FGFR2REACTOMER-HSA-5654738
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
FGFR2 alternative splicingREACTOMER-HSA-6803529

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381950172024Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition.0
381950172024Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition.0
373994012023The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells.5
373994012023The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells.5
333499592021Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.33
333499592021Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.33
314031842020Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing.25
314031842020Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing.25
303126832019Heterogeneous ribonucleoprotein F regulates YAP expression via a G-tract in 3'UTR.4
312215862019HnRNP-F regulates EMT in bladder cancer by mediating the stabilization of Snail1 mRNA by binding to its 3' UTR.30
303126832019Heterogeneous ribonucleoprotein F regulates YAP expression via a G-tract in 3'UTR.4
312215862019HnRNP-F regulates EMT in bladder cancer by mediating the stabilization of Snail1 mRNA by binding to its 3' UTR.30
297736552018FOXP3 interacts with hnRNPF to modulate pre-mRNA alternative splicing.11
301156312018TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency.43
304681062018Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K in breast cancer cells.24

Citation

Dessen P

HNRNPF (heterogeneous nuclear ribonucleoprotein F)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43592/js/img/logo-atlas-4.svg