TUBA1B (tubulin alpha 1b)

2007-02-01  

Identity

HGNC
TUBA1B
LOCATION
12q13.12
LOCUSID
10376
ALIAS
K-ALPHA-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10376
MIM: 602530
HGNC: 18809
Ensembl: ENSG00000123416

Variants:

dbSNP: 10376
ClinVar: 10376
TCGA: ENSG00000123416
COSMIC: TUBA1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123416ENST00000336023P68363
ENSG00000123416ENST00000547476F8VX09
ENSG00000123416ENST00000547765F8VU66
ENSG00000123416ENST00000549870F8VWV9
ENSG00000123416ENST00000550367F8VVB9
ENSG00000123416ENST00000552984F8VRK0

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
ApoptosisKEGGko04210
Tight junctionKEGGko04530
Gap junctionKEGGko04540
Pathogenic Escherichia coli infectionKEGGko05130
ApoptosisKEGGhsa04210
Tight junctionKEGGhsa04530
Gap junctionKEGGhsa04540
Pathogenic Escherichia coli infectionKEGGhsa05130
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Metabolism of proteinsREACTOMER-HSA-392499
Protein foldingREACTOMER-HSA-391251
Chaperonin-mediated protein foldingREACTOMER-HSA-390466
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingREACTOMER-HSA-389958
Formation of tubulin folding intermediates by CCT/TriCREACTOMER-HSA-389960
Post-chaperonin tubulin folding pathwayREACTOMER-HSA-389977

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
373792092023Integrated regulation of tubulin tyrosination and microtubule stability by human α-tubulin isotypes.2
374892562023Tubulin Alpha-1b as a Potential Biomarker for Lung Adenocarcinoma Diagnosis and Prognosis.0
373792092023Integrated regulation of tubulin tyrosination and microtubule stability by human α-tubulin isotypes.2
374892562023Tubulin Alpha-1b as a Potential Biomarker for Lung Adenocarcinoma Diagnosis and Prognosis.0
342749032021Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder.4
344341882021Dynamic Network Biomarker of Pre-Exhausted CD8(+) T Cells Contributed to T Cell Exhaustion in Colorectal Cancer.13
342749032021Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder.4
344341882021Dynamic Network Biomarker of Pre-Exhausted CD8(+) T Cells Contributed to T Cell Exhaustion in Colorectal Cancer.13
317676812020Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.22
329089312020The Expression and Potential Role of Tubulin Alpha 1b in Wilms' Tumor.7
317676812020Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.22
329089312020The Expression and Potential Role of Tubulin Alpha 1b in Wilms' Tumor.7
282906712017Mobility and Core-Protein Binding Patterns of Disordered C-Terminal Tails in β-Tubulin Isotypes.8
282906712017Mobility and Core-Protein Binding Patterns of Disordered C-Terminal Tails in β-Tubulin Isotypes.8
266760542016Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling.15

Citation

Dessen P

TUBA1B (tubulin alpha 1b)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43596/js/lib/css/card-gene.css